; RUN: opt < %s -passes=instcombine -S | grep icmp ; PR1646 @__gthrw_pthread_cancel = weak alias i32 (i32), i32 (i32)* @pthread_cancel ; <i32 (i32)*> [#uses=1] @__gthread_active_ptr.5335 = internal constant i8* bitcast (i32 (i32)* @__gthrw_pthread_cancel to i8*) ; <i8**> [#uses=1] define weak i32 @pthread_cancel(i32) { ret i32 0 } define i1 @__gthread_active_p() { entry: %tmp1 = load i8*, i8** @__gthread_active_ptr.5335, align 4 ; <i8*> [#uses=1] %tmp2 = icmp ne i8* %tmp1, null ; <i1> [#uses=1] ret i1 %tmp2 }