apraga/org - Change DLVDDDQM5KLVARTTRQFGT234AQT7X65VGPQULMDZ7K2ABH5F6GZAC

Antibio update

Created by Alexis Praga on September 11, 2023

DLVDDDQM5KLVARTTRQFGT234AQT7X65VGPQULMDZ7K2ABH5F6GZAC

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Change contents

Replacement in notes/medecine/diarrhees.org at line 28 [6.134]

B:BD[5.385] → [5.385:566]

- *pas d’antibiogramme* = sensible métronidazoe + vanco
- hygène = *contact*, iselemnt, lavage *mécanique* des mains, *Javel*. Isolement levé 48h après arrêt des diarrhées

[5.385]

[7.329]

- *pas d’antibiogramme* = sensible métronidazole + vanco
- hygène = *contact*, isolement, lavage *mécanique* des mains, *Javel*. Isolement levé 48h après arrêt des diarrhées

Insertion in notes/medecine/20230528235406-antibiotiques.org at line 141 [9.138]

[4.1328]

[8.6898]

* Note
- résistance érythromycine et sensible à la clindamycine : si inductible, possible sélection de mutant  ?

Replacement in notes/medecine/20230528225531-bacteries.org at line 6 [9.10483]

B:BD[9.10601] → [10.146:498]

∅:D[10.498] → [9.10601:10649]

B:BD[9.10601] → [9.10601:10649]

* Résistante
PLP = paroi externe de la membrane plasmique. Sert à synthétisé le peptidoglycane = composant de la paroi. Les beta-lactamine vont inhiber la synthèse de peptidoglycane. En cas de PLP2a, moins d’affinité aux beta-lactamine.
https://pharmacomedicale.org/medicaments/par-specialites/item/beta-lactamines-penicillines-cephalosporines
* Bactéries
** Staphylocoques
*** Résistances

[9.10601]

[10.499]

* Staphylocoques
** Résistances

Replacement in notes/medecine/20230528225531-bacteries.org at line 17 [9.10483]
∅:D[10.1113] → [9.11086:11112]
B:BD[9.11086] → [9.11086:11112]
```
*** Staphylococcus aureus
```
[10.1113]
[9.11112]
```
** Staphylococcus aureus
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 20 [9.10483]
B:BD[9.11198] → [9.11198:11225]
```
**** Facteurs de virulence
```
[9.11198]
[9.11225]
```
*** Facteurs de virulence
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 35 [9.10483]
B:BD[9.11937] → [9.11937:11950]
```
**** Habitat
```
[9.11937]
[9.11950]
```
*** Habitat
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 40 [9.10483]
B:BD[9.12145] → [9.12145:12159]
```
**** Clinique
```
[9.12145]
[9.12159]
```
*** Clinique
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 52 [9.10483]
B:BD[9.12783] → [9.12783:12799]
```
**** Diagnostic
```
[9.12783]
[9.12799]
```
*** Diagnostic
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 57 [9.10483]
B:BD[9.13028] → [9.13028:13061]
```
**** Sensibilité et résistance
```
[9.13028]
[9.13061]
```
*** Sensibilité et résistance
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 67 [9.10483]
B:BD[9.13682] → [3.458:496]
```
**** Traitement habituellement actifs
```
[9.13682]
[3.496]
```
*** Traitement habituellement actifs
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 69 [9.10483]
B:BD[3.560] → [3.560:590]
```
*** Staphylococcus non aureus
```
[3.560]
[3.590]
```
** Staphylococcus non aureus
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 77 [9.10483]
B:BD[3.1005] → [3.1005:1039]
```
**** Staphylococcus saprophyticus
```
[3.1005]
[9.13715]
```
*** Staphylococcus saprophyticus
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 83 [9.10483]
B:BD[9.14068] → [11.152:169]
```
** Campylobacter
```
[9.14068]
[11.169]
```
* Campylobacter
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 89 [9.10483]
∅:D[3.1168] → [11.440:463]
∅:D[7.1573] → [11.440:463]
B:BD[11.440] → [11.440:463]
```
*** Pouvoir pathogène
```
[3.1168]
[11.463]
```
** Pouvoir pathogène
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 95 [9.10483]
∅:D[3.1215] → [11.662:687]
B:BD[11.662] → [11.662:687]
```
*** Diagnostic bactério
```
[3.1215]
[11.687]
```
** Diagnostic bactério
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 102 [9.10483]
B:BD[11.906] → [11.906:920]
```
*** ATBgramme
```
[11.906]
[3.1250]
```
** ATBgramme
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 105 [9.10483]
∅:D[12.319] → [11.1080:1095]
B:BD[11.1080] → [11.1080:1095]
```
*** Traitement
```
[12.319]
[11.1095]
```
** Traitement
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 109 [9.10483]
∅:D[12.387] → [11.1283:1329]
∅:D[3.1532] → [11.1283:1329]
B:BD[11.1283] → [11.1283:1329]
∅:D[11.1329] → [9.14068:14089]
B:BD[9.14068] → [9.14068:14089]
```
*** Prévention: hygiène (eau, alimentation)
** Proteus mirabilis
```
[3.1532]
[13.2439]
```
** Prévention: hygiène (eau, alimentation)
* Proteus mirabilis
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 116 [9.10483]
∅:D[12.652] → [9.14089:14120]
∅:D[13.2782] → [9.14089:14120]
B:BD[9.14089] → [9.14089:14120]
```
** TODO Pseudomonas aeruginosa
```
[12.652]
[9.14120]
```
* TODO Pseudomonas aeruginosa
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 127 [9.10483]
B:BD[9.14399] → [14.8782:8819]
```
*** Quand réaliser un antibiogramme
```
[9.14399]
[14.8819]
```
** Quand réaliser un antibiogramme
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 131 [9.10483]
∅:D[14.8953] → [9.14400:14415]
B:BD[9.14400] → [9.14400:14415]
```
*** Diagnostic
```
[14.8953]
[9.14415]
```
** Diagnostic
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 135 [9.10483]
B:BD[9.14574] → [9.14574:14590]
```
*** Résistance
```
[9.14574]
[14.8954]
```
** Résistance
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 139 [9.10483]
B:BD[14.9054] → [14.9054:9083]
```
**** Résistance naturelle :
```
[14.9054]
[14.9083]
```
*** Résistance naturelle :
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 153 [9.10483]
B:BD[14.9522] → [14.9522:9547]
```
**** Résistance acquise
```
[14.9522]
[14.9547]
```
*** Résistance acquise
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 166 [9.10483]
B:BD[14.9978] → [14.9978:9996]
```
**** Antibiotique
```
[14.9978]
[14.9996]
```
*** Antibiotique
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 176 [9.10483]
∅:D[15.488] → [9.14730:14747]
∅:D[14.10247] → [9.14730:14747]
B:BD[9.14730] → [9.14730:14747]
```
** Streptocoques
```
[14.10247]
[16.35086]
```
* Streptocoques
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 179 [9.10483]
∅:D[7.1653] → [9.14748:14767]
∅:D[16.35209] → [9.14748:14767]
B:BD[9.14748] → [9.14748:14767]
```
*** Classification
```
[7.1653]
[16.35210]
```
** Classification
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 194 [9.10483]
∅:D[16.35821] → [9.15232:15249]
B:BD[9.15232] → [9.15232:15249]
```
*** Résistances
```
[16.35821]
[17.2186]
```
** Résistances
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 201 [9.10483]
∅:D[17.2537] → [16.35822:35852]
∅:D[18.9955] → [16.35822:35852]
B:BD[9.15379] → [16.35822:35852]
```
*** Classification d’Ambler
```
[18.9955]
[16.35852]
```
** Classification d’Ambler
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 214 [9.10483]
∅:D[16.36263] → [9.15379:15408]
B:BD[9.15379] → [9.15379:15408]
```
*** Streptococcocus pyogenes
```
[16.36263]
[9.15408]
```
** Streptococcocus pyogenes
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 218 [9.10483]
B:BD[9.15558] → [9.15558:15591]
```
**** Facteurs de pathogénicité
```
[9.15558]
[9.15591]
```
*** Facteurs de pathogénicité
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 227 [9.10483]
∅:D[2.3169] → [9.15978:15991]
B:BD[9.15978] → [9.15978:15991]
```
**** Habitat
```
[2.3169]
[9.15991]
```
*** Habitat
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 230 [9.10483]
B:BD[9.16098] → [9.16098:16112]
```
**** Clinique
```
[9.16098]
[7.1683]
```
*** Clinique
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 235 [9.10483]
B:BD[9.16478] → [9.16478:16494]
```
**** Diagnostic
```
[9.16478]
[9.16494]
```
*** Diagnostic
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 240 [9.10483]
B:BD[9.16640] → [9.16640:16671]
```
**** Sensibilité, résistance
```
[9.16640]
[9.16671]
```
*** Sensibilité, résistance
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 243 [9.10483]
B:BD[9.16794] → [19.294:322]
```
*** TODO Strepto agalactiae
```
[9.16794]
[7.1817]
```
** TODO Strepto agalactiae
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 248 [9.10483]
B:BD[5.1056] → [5.1056:1071]
```
**** Bactério
```
[5.1056]
[5.1071]
```
*** Bactério
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 254 [9.10483]
B:BD[5.1194] → [5.1194:1215]
```
**** Pathogènicité
```
[5.1194]
[5.1215]
```
*** Pathogènicité
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 263 [9.10483]
B:BD[5.1602] → [5.1602:1619]
```
**** Résistance
```
[5.1602]
[5.1619]
```
*** Résistance
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 268 [9.10483]
B:BD[5.1761] → [5.1761:1777]
```
**** Diagnostic
```
[5.1761]
[5.1777]
```
*** Diagnostic
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 275 [9.10483]
B:BD[5.2022] → [5.2022:2039]
```
**** Prévention
```
[5.2022]
[5.2039]
```
*** Prévention
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 279 [9.10483]
∅:D[7.2002] → [17.2567:2591]
∅:D[5.2132] → [17.2567:2591]
B:BD[19.360] → [17.2567:2591]
```
*** Strepto. pneumoniae
```
[7.2002]
[9.16810]
```
** Strepto. pneumoniae
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 282 [9.10483]
B:BD[9.16913] → [9.16913:16926]
```
**** Habitat
```
[9.16913]
[17.2592]
```
*** Habitat
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 285 [9.10483]
B:BD[9.16993] → [9.16993:17014]
```
**** Pathogénicité
```
[9.16993]
[17.2623]
```
*** Pathogénicité
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 290 [9.10483]
B:BD[9.17181] → [9.17181:17198]
```
**** Résistance
```
[9.17181]
[9.17198]
```
*** Résistance
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 295 [9.10483]
∅:D[17.2858] → [9.17342:17356]
B:BD[9.17342] → [9.17342:17356]
```
**** Clinique
```
[17.2858]
[9.17356]
```
*** Clinique
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 300 [9.10483]
B:BD[9.17613] → [9.17613:17661]
```
** Entérobactéries
*** Résistances et groupe
```
[9.17613]
[9.17661]
```
* Entérobactéries
** Résistances et groupe
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 310 [9.10483]
B:BD[9.18082] → [9.18082:18103]
```
*** Escherichia coli
```
[9.18082]
[9.18103]
```
** Escherichia coli
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 317 [9.10483]
∅:D[7.2142] → [13.3112:3157]
B:BD[13.3112] → [13.3112:3157]
```
*** KES = Klebsiella, ENterobacter, Serratia
```
[7.2142]
[13.3157]
```
** KES = Klebsiella, ENterobacter, Serratia
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 319 [9.10483]
∅:D[13.3181] → [20.151:176]
B:BD[9.18506] → [20.151:176]
```
*** Salmonelle, Shigelle
```
[13.3181]
[20.176]
```
** Salmonelle, Shigelle
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 329 [9.10483]
B:BD[20.592] → [20.592:616]
```
**** Pouvoir pathègene
```
[20.592]
[20.616]
```
*** Pouvoir pathègene
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 334 [9.10483]
B:BD[20.849] → [20.849:865]
```
**** Physiopath
```
[20.849]
[20.865]
```
*** Physiopath
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 343 [9.10483]
B:BD[20.1407] → [20.1407:1423]
```
**** Diagnostic
```
[20.1407]
[20.1423]
```
*** Diagnostic
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 354 [9.10483]
B:BD[20.1806] → [20.1806:1822]
```
**** Traitement
```
[20.1806]
[20.1822]
```
*** Traitement
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 365 [9.10483]
∅:D[20.2221] → [17.2859:2876]
B:BD[9.18506] → [17.2859:2876]
```
** Entérocoques
```
[20.2221]
[9.18524]
```
* Entérocoques
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 369 [9.10483]
B:BD[9.18654] → [17.2877:2889]
```
*** Habitat
```
[9.18654]
[9.18667]
```
** Habitat
```
Replacement in notes/medecine/20230528225531-bacteries.org at line 377 [9.10483]
B:BD[17.2990] → [17.2990:3016]
```
*** Facteurs de virulence
```
[17.2990]
[9.18914]
```
** Facteurs de virulence
```

Replacement in notes/medecine/20230528225531-bacteries.org at line 380 [9.10483]

B:BD[9.19063] → [17.3017:3063]

B:BD[17.3063] → [13.3182:3268]

∅:D[13.3268] → [17.3063:3127]

B:BD[17.3063] → [17.3063:3127]

*** Résistance
- Naturelle : céphalosporine
  - faecals = résistance oxacilline, C3G, ertapénème, lincomycine, acide fusidique
- *E. faecalis = sensible amox. E. faecium = résistant 80-90%*

[9.19063]

[17.3127]

** Résistance
- Naturelle : *céphalosporine*
  - faecalis = résistance oxacilline, C3G, ertapénème, lincomycine, acide fusidique
- *E. faecalis = sensible amox*. E. faecium = résistant 80-90%*

Replacement in notes/medecine/20230528225531-bacteries.org at line 389 [9.10483]

∅:D[17.3289] → [9.19294:19373]

B:BD[9.19294] → [9.19294:19373]

B:BD[9.19373] → [17.3290:3303]

Attention: en cas de résistance surajoutée, les aminosides sont inefficaces.
*** Clinique

[17.3289]

[9.19387]

- en cas de résistance surajoutée, les aminosides sont inefficaces.
- attention aux entérococques résistant vancomycine (surtout E. faecium): /vancA/ /vancB/
** Clinique

Replacement in notes/medecine/20230528225531-bacteries.org at line 397 [9.10483]

B:BD[9.19509] → [17.3304:3321]

∅:D[17.3321] → [9.19527:19740]

B:BD[9.19527] → [9.19527:19740]

B:BD[9.19740] → [17.3322:3330]

∅:D[21.266] → [9.19740:19741]

∅:D[17.3330] → [9.19740:19741]

B:BD[9.19740] → [9.19740:19741]

B:BD[9.19741] → [21.267:536]

∅:D[22.204] → [9.19741:19767]

∅:D[21.536] → [9.19741:19767]

∅:D[23.55576] → [9.19741:19767]

B:BD[9.19741] → [9.19741:19767]

*** Résistances
- résistance naturelle céphalosporine
- E. faecalis : pas résistance pénicilline A (contrairement à E. faecium)
- E. faecium :
  - multiréristance en émergence
  - > 80% faecium résistance pénicillines A
*** lol
Clinique
- infection urinaire: le plus fréquent, nosocomial
- bactériémie
- endocardite : de plus en plus fréquent
- infection intra-abdominal (en association)
Résistance: attention aux entérococques résistant vancomycine (surtout E. faecium)
- /vancA/ /vancB/
** Neisseria meningitidis

[9.19509]

[9.19767]

* Neisseria meningitidis

Replacement in notes/medecine/20230528225531-bacteries.org at line 402 [9.10483]

B:BD[9.19945] → [9.19945:20022]

  - ceinture de la ménigitde (Afrique sahel + subusaharanienne)
*** Habitat

[9.19945]

[9.20022]

  - ceinture de la méningite (Afrique sahel + subusaharienne)
** Habitat

Replacement in notes/medecine/20230528225531-bacteries.org at line 406 [9.10483]

B:BD[9.20177] → [9.20177:20286]

B:BD[9.20286] → [15.489:519]

** Listeria monocytègene
*** Résistance
- résistance naturelle céphalosporine, clindamycine, fosfomycine
** TODO Haemophilus influenza

[9.20177]

[15.519]

* Listeria monocytègene
Résiste à 4° !
^
** Clinique
- non invasive = gastro
- invasive: *bactériémie*, neurolistériose, infection materno-foetale avec forme néonatale précoce ou > 7j
** Diagnostic
- hémoc, PL
- non exigeant
** Résistance
- résistance naturelle *C3G*, fosfomycine, quinolone
** Traitement
- amox + genta
* TODO Haemophilus influenza

Replacement in notes/medecine/20230528225221-classification_bacteries.org at line 13 [9.20341]

B:BD[9.20669] → [9.20669:20742]

#+BEGIN_SRC dot :file ../images/microbiologie/aerobies.png :exports none

[9.20669]

[9.20742]

#+BEGIN_SRC dot :file ../../images/microbiologie/aerobies.png :exports none

Replacement in notes/medecine/20230528225221-classification_bacteries.org at line 37 [9.20341]

B:BD[9.21516] → [9.21516:21768]

              "Entérobactéries\nE. coli, Klebsiella\nEnterobacter\nSerratia\nPretous\nSalmonella\nShigella\nYersinia\nCitrobacter"
              "Autres:\nPseudomonas\nStenotrophomonoas\nAcinetobacter\nCampolybacter\nVibrio\nBordetella\Haemophilius"

[9.21516]

[9.21768]

              "Entérobactéries\nE. coli, Klebsiella\nEnterobacter\nSerratia\nProteus\nSalmonella\nShigella\nYersinia\nCitrobacter"
              "Autres:\nPseudomonas\nStenotrophomonoas\nAcinetobacter\nCampolybacter\nVibrio\nBordetella\nHaemophilius"

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#+BEGIN_SRC dot :file ../images/microbiologie/anaerobies.png :exports none

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#+BEGIN_SRC dot :file ../../images/microbiologie/anaerobies.png :exports none

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```
#+BEGIN_SRC dot :file ../images/microbiologie/autres.png :exports none
```
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```
#+BEGIN_SRC dot :file ../../images/microbiologie/autres.png :exports none
```
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Antibio update

Dependencies

In channels

Change contents

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